Annals of Internal Medicine | SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials

SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials

vía Annals of Internal Medicine | SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical Trials.

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The protocol of a clinical trial serves as the foundation for study planning, conduct, reporting, and appraisal. However, trial protocols and existing protocol guidelines vary greatly in content and quality. This article describes the systematic development and scope of SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013, a guideline for the minimum content of a clinical trial protocol.

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