Publication of NIH funded trials registered in ClinicalTrials.gov: cross sectional analysis | BMJ

Publication of NIH funded trials registered in ClinicalTrials.gov: cross sectional analysis

BMJ 2012; 344 doi: 10.1136/bmj.d7292 (Published 3 January 2012)

vía Publication of NIH funded trials registered in ClinicalTrials.gov: cross sectional analysis | BMJ.

Abstract

Objective To review patterns of publication of clinical trials funded by US National Institutes of Health (NIH) in peer reviewed biomedical journals indexed by Medline.

Design Cross sectional analysis.

Setting Clinical trials funded by NIH and registered within ClinicalTrials.gov (clinicaltrials.gov), a trial registry and results database maintained by the US National Library of Medicine, after 30 September 2005 and updated as having been completed by 31 December 2008, allowing at least 30 months for publication after completion of the trial.

Main outcome measures Publication and time to publication in the biomedical literature, as determined through Medline searches, the last of which was performed in June 2011.

Results Among 635 clinical trials completed by 31 December 2008, 294 (46%) were published in a peer reviewed biomedical journal, indexed by Medline, within 30 months of trial completion. The median period of follow-up after trial completion was 51 months (25th-75th centiles 40-68 months), and 432 (68%) were published overall. Among published trials, the median time to publication was 23 months (14-36 months). Trials completed in either 2007 or 2008 were more likely to be published within 30 months of study completion compared with trials completed before 2007 (54% (196/366) v 36% (98/269); P<0.001).

Conclusions Despite recent improvement in timely publication, fewer than half of trials funded by NIH are published in a peer reviewed biomedical journal indexed by Medline within 30 months of trial completion. Moreover, after a median of 51 months after trial completion, a third of trials remained unpublished.

Una respuesta to “Publication of NIH funded trials registered in ClinicalTrials.gov: cross sectional analysis | BMJ”

  1. Immigration Advice Chelmsford Says:

    When I originally commented I clicked the “Notify me when new comments are added” checkbox and now
    each time a comment is added I get three e-mails with
    the same comment. Is there any way you can remove me from that service?
    Thanks a lot!

Responder

Introduce tus datos o haz clic en un icono para iniciar sesión:

Logo de WordPress.com

Estás comentando usando tu cuenta de WordPress.com. Cerrar sesión / Cambiar )

Imagen de Twitter

Estás comentando usando tu cuenta de Twitter. Cerrar sesión / Cambiar )

Foto de Facebook

Estás comentando usando tu cuenta de Facebook. Cerrar sesión / Cambiar )

Google+ photo

Estás comentando usando tu cuenta de Google+. Cerrar sesión / Cambiar )

Conectando a %s


A %d blogueros les gusta esto: